10 results
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
AIHA • Anemia ... ↑ LDH • Anti-RBC ... C3d • Blood smear ... 2) LOOK FOR a cause ... #management #treatment
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Peripheral blood smear ... Hypochromic & microcytic RBCs ... #causes
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
Algorithm for the ... (RBC = red blood ... ordering a peripheral smear ... Hemorrhage or hemolysis ... #Workup #AAFP
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... Peripheral blood smear ... schistocytes, nucleated RBCs ... anemia Indirect ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Hematologic disease caused ... lysis → severe hemolytic ... anemia, jaundice ... phase: Peripheral smear ... TREATMENT: ​• Acute
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Peripheral Smear ... hematology for workup ... blood loss, Acute hemolysis ... , deficiency anemia ... Rebound effect from treatment
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... formed or don’t work ... Peripheral Smear ... Workup: • Complete ... Peripheral blood smear
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
Hgb 12.5, WBC 14 ... Treatment is tetracycline ... initiation of treatment ... recurrentis #BloodSmear #microscopy ... #pathology #clinical
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... nodosum • Immune hemolytic ... anemia • Pain ... Hodgkin Lymphoma Workup ... Hodgkin Lymphoma Treatment
Fever After International Travel

Infectious Disease:
• Endemic in either the destination or home region

Viral Syndromes:
Arboviral infections, a
infections, a common cause ... No hemolytic anemia ... Investigations: • CBC ... chest film; blood-smear ... dipstick test, microscopic