12 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... - CHAMPS Mnemonic ... S - Systemic Lupus ... Hypocomplementemia #Low #Complement ... #CHAMPS #Mnemonic
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
cases, drug-dependent ... 90% - Low complement ... Discontinuation of causal ... Erythematosus (SLE ... 80% - Low complement
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... Positive in 60-80% of cases ... 80% - Low complement ... #lupus #Systemic
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Post-strep GN, Lupus ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Causes of Recurrent Pregnancy Loss - Differential Diagnosis Algorithm
Environmental:
 • Toxin (organic solvents, mercury, lead)
 •
Causes of Recurrent ... Differential Diagnosis Algorithm ... Antiphospholipid syndrome • Lupus ... #Causes #Obstetrics ... #OBGyn
Causes of Pelvic Mass - Differential Diagnosis Algorithm
Gastrointestinal:
 • Appendiceal abscess
 • Diverticular abscess
 • Diverticulosis
Causes of Pelvic ... Differential Diagnosis Algorithm ... Hydrosalpinx Ovary: • See ... #Causes #Gynecology ... #OBGyn
Factors that May Affect Fetal Oxygenation - Differential Diagnosis Algorithm

Excessive Uterine Activity:
 • Hyperstimulation
 • Placental
Differential Diagnosis Algorithm ... Vasculopathy (SLE ... Differential #Diagnosis #Algorithm ... #Causes #Obstetrics ... #OBGyn
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... (e.g. systemic lupus ... erythematosus (SLE
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
Lupus Nephritis ... with systemic lupus ... , WBC casts) especially ... Disease (5%) #Lupus ... Nephritis #diagnosis #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement ... vasculitis, and SLE