37 results
diagnosis differential rheumatology causes sle classification erythematosus algorithm management hematology pathophysiology arthritis cardiology comparison msk table types vasculitis allergy criteria
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Hypocomplementemia - CHAMPS ... glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... Hypocomplementemia #Low #Complement ... #CHAMPS #Mnemonic
Systemic Lupus Erythematosus (SLE): Pathogenesis • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Systemic Lupus Erythematosus ... HLA-DR3 genes, complement ... self-antigens, activating complement ... Abnormal release of inflammatory ... #Lupus #Erythematosus
Seronegative Inflammatory Arthritis - Differential Diagnosis • Seronegative Rheumatoid Arthritis • Infectious Arthritis: Viral, Bacterial,
Seronegative Inflammatory ... Lupus Erythematous ... , Systemic Sclerosis ... Still's Disease, Inflammatory ... #Seronegative #Inflammatory
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Inflammatory Cascade ... dead tissue • Complement ... System: opsonize ... activation of complement ... system • Cell-mediated
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Classification Criteria for Systemic ... Lupus Erythematosus ... Acute cutaneous lupus ... anticoagulant • Complement ... Criteria #SLE #Systemic
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... 80% - Low complement ... Lupusreference #SLE #lupus ... #Systemic #Erythematosus
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... Complement activation ... provides inflammatory ... arthritis, and systemic ... lupus erythematosus
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
Diagnostic Criteria - Systemic ... Lupus Erythematosus ... ACUTE CUTANEOUS LUPUS ... CHRONIC CUTANEOUS LUPUS ... anticoagulant - Low complement
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... , Drug-induced Lupus ... lupus erythematosus ... lupus erythematosus ... Drug-Induced, Inflammatory
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
psoriasis (7-30%) • Inflammatory ... pannus formation, systemic ... Polyarthritis • Systemic ... Lupus - with Systemic ... Lupus Erythematosus
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