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diagnosis treatment hematology syndrome arteritis dermatology fusarium gca giantcell infections lupus sle 2ndline antinxp2 antinxp2dm aspergillus blood capillary cerebritis clarksons
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
suspected) • In case ... • Special cases ... (e.g. renal failure ... Measurement #SLE #rheumatology ... levels #lupus #management
Visceral Leishmaniasis - Diagnosis and Management Summary Species: Leishmania donovani, Leishmania infantum, Leishmania chagasi Where: South Asia, East
Diagnosis and Management ... Weight Loss • Can cause ... total of 21 mg/kg ... Leishmaniasis #diagnosis #management ... #treatment #infectiousdiseases
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... normal in mild cases ... hemophilia type (e.g ... Chronic Management ... #treatment #hematology
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
Diagnosis and Management ... infections are caused ... immunosuppression (eg ... IA #Diagnosis #Management ... treatment #fungal #infectiousdiseases
Treatment of giant cell arteritis (GCA) 1st Line Strategy - GC 0.7 mg/kg/day, except for: • Aortitis
Strategy - GC 0.7 mg/kg ... dissection - 1 mg/kg ... MTX or TCZ in case ... GCA #Treatment #Management ... #Indications #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
not be subtle e.g ... identifies 85 to 95% of cases ... per day or 1 mg/kg ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Toxic Alcohol Ingestion: Methanol Solvent found in cleaning and printing solutions, adhesives, stains, paint removers, antifreeze agent in
dose = 1-2 mL/kg ... . formic acid) causes ... , but does NOT cause ... #Diagnosis #Management ... Methanol #Ingestion #ALiEM
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... antiinflammatory properties e.g ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
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