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diagnosis hematology classification algorithm fever hemolytic infections infectiousdiseases workup agglutinin biliary cholangitis cirrhosis cold dermatology elevation gap globulin hepatitis injury
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... • Bleeding • Hemolysis ... Renal Disease, Liver ... #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... : • Liver disease ... HUS, DIC, HELLP, AS ... #Anemia #Differential
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Grafts, Valves, AS ... Drug-associated, PCH ... Defects, Drugs, Liver ... Defects: Sickle cell anemia
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Algorithm Vascular Causes ... Bilirubin: RBC (hemolysis ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
anemia • Cold ... younger pts) Differential ... Disorders Such As ... #hemolytic #anemia ... #hematology #diagnosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... cholestasis → Cirrhosis/Liver ... or higher • Liver ... bile ducts Differential ... diagnosis #workup #hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... result in severe anemia ... Haptoglobin - Low as ... anemia Indirect ... WBC count and differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... deficiency • Liver ... #Diagnosis #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential ... www.ncbi.nlm.nih.gov/pmc ... presentations and disease ... 30mmHg) - Severe anemia ... #Elevation #Differential
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Fever Patterns - Differential ... Non-Infectious Causes ... (Temp high in AM ... with profound hemolysis ... Brucellosis • Liver
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