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hematology differential hepatorenal hrs mgus oncology syndrome alkaline alp complications gammopathies gammopathy gap globulin hrsaki hrsckd hrsnaki hyophosphatasia low multiplemyeloma
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
dL the ULN R - Renal ... Causes of false- ... amyloidosis Other causes ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
Syndrome (HRS) - Diagnostic ... haematuria, Normal renal ... ultrasound HRS-NAKI ... - No other cause ... HRSAKI #HRSNAKI #hepatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Entities That Can Feature ... A Monoclonal Protein ... vascular beds-renal ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... • recurrent fractures ... : - Renal failure ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS) Fracture, Osteoporosis - Increased osteoclast activity and bone resorption
Complications of Monoclonal ... Significance (MGUS) Fracture ... ; vaccinations Renal ... Complications #diagnosis ... #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
it represents a monoclonal ... Causes of Monoclonal ... cancers, HCC, renal ... #differential #diagnosis ... #hematology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
• Caused by splanchnic ... vasodilation → ↓ renal ... perfusion + ↑ renal ... Normal kidney ultrasound ... Hepatorenal #Syndrome #Hepatology
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