9 results
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
venous gas on hepatic ... ultrasound: A concerning ... distension (i.e. ileus ... variety of other causes ... #hepatology #liver
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... ASA) • Renal Disease ... Iatrogenic) • Liver ... Deficiency • Disseminated ... #Hematology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Highest • Bone • Liver ... Intestine - Other causes ... Pregnancy - Renal ... elevation DDX of Hepatic ... Diagnosis #Algorithm #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Disseminated Intravascular ... Bleeding (64%) • Renal ... DIC • Severe Liver ... Treat primary cause ... treatment #management #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
(e.g. heparin contamination ... thrombin inhibitors, heparin ... • Reduced liver ... hemorrhage • Disseminated ... #differential #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... Disseminated intravascular ... #differential #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Syndrome, Ischemic Liver ... Hyperhomocysteinemia - Heparin-induced ... thrombocytopenia - Disseminated ... coagulation and other causes ... pathophysiology #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... • recurrent fractures ... neuropathy • Renal ... : - Renal failure ... Hyophosphatasia #hepatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Acquired: • Heparin ... failure, disseminated ... discern these causes ... are liver function ... Differential #Diagnosis #Hematology