39 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Systemic Sclerosis (Scleroderma ... calcinosis • Pulmonary ... disease), PAH (pulmonary ... #SSc #rheumatology ... #diagnosis #signs
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... Telangiectasia • Scleroderma ... • Scleroderma ... #differential #diagnosis ... #rheumatology
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
Scleroderma Like ... - Differential Diagnosis ... #Differential #Diagnosis ... #comparison #table ... #dermatology
Differential diagnosis of Skin + Eye infections
 • Bacterial: Staph spp, Strep spp, Pseudomonas spp, Bartonella,
Differential diagnosis ... of Skin + Eye infections ... febrilepodcast] #skin ... #eye #ocular #dermatology ... #InfectiousDiseases
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
anti-Sc170): Diffuse skin ... disease, Pulmonary ... disease (~93-95%), Pulmonary ... Autoantibodies #diagnosis ... #rheumatology
Diagnostic Criteria for Scleroderma Renal Crisis 

1. New onset blood pressure >150/85 mm Hg OR increase
Diagnostic Criteria ... for Scleroderma ... anuria - Flash pulmonary ... including onion skin ... Renal #Crisis #Diagnosis
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... TIF1y, MDA5 • Scleroderma ... Autoantibodies #Rheumatology ... #diagnosis #associations ... #table
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
systemic sclerosis/scleroderma ... systemic sclerosis/scleroderma ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anti-Scl-70 - Scleroderma ... Associations #diseases #diagnosis ... #table #rheumatology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
LungDisease #CTILD #Diagnosis ... Differential #Comparison #Table ... #Pulmonary #Rheumatology