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diagnosis hematology causes algorithm management workup classification hemolytic thrombocytopenia arthritis joint neurology oncology pancytopenia thrombocytosis approach cardiology chronic hemolysis pain
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - Differential ... Reactive: • Anemia ... deficiency) • Infection ... Sepsis • Non-infectious ... (malignancy, rheumatologic
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Pelger-Huet, Macrocytic anemia ... Amy Chung, MD, MSc ... #hematology #Markers ... #Differential #
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... - Differential ... Hypersplenism, Infection ... #Differential # ... Diagnosis #Algorithm #hematology
Causes of Hemolytic Anemia - Differential Diagnosis Inherited • Membrane • Internal - Hemoglobin
Causes of Hemolytic Anemia ... - Differential ... Internal - Infectious ... #Differential # ... Diagnosis #Causes #hematology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Anemia - Underproduction ... Iron deficiency anemia ... Probable bone marrow disorder ... Underproduction #Algorithm #hematology ... #diagnosis #differential
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Neutrophils - Differential ... Diagnosis Algorithm Infection ... • Metabolic disorders ... Myeloproliferative Disorder ... Algorithm #Causes #Hematology
Approach to a Positive (+) Rheumatoid Factor (RF) (+) RF does not always = RA Rheumatic disorders: •
RA Rheumatic disorders ... : • Chronic infections ... • Inflammatory disorders ... Rheumatoid #Factor #RF #rheumatology ... #laboratory #differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Thrombocytosis - Differential ... Myelofibrosis Infectious ... • Rheumatic disorders ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... Thrombocytosis): • Acute infection ... malignancies • Anemia ... Chronic inflammatory disorders ... Diagnosis #Causes #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... • RBC Membrane Disorder ... RBC Metabolism Disorder ... Classification #Approach #Differential ... Algorithm #Causes #Hematology
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