76 results
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Pathologic / Fragility Fractures ... - Differential Diagnosis ... • Vitamin D Deficiency ... #Pathologic #MSK ... #Orthopedics #Causes
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Differential Diaqnoses ... mevalonate kinase deficiency ... #diagnosis #management ... #treatment #rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... and clinical associations ... and duration of symptoms ... angioedema Other symptoms ... #rheumatology #
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Pathogenesis and clinical ... Greater Trochanter Fracture ... pathophysiology #causes ... #symptoms #signs ... #diagnosis #msk
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... Malnutrition • Wilson's disease ... mineralization Symptoms ... Phosphatase: • Other causes
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... (MS), Epidural ... heavy metals), Critical ... : Acid maltase deficiency ... #differential #diagnosis
Krabbe Disease 

Check out this interesting case of Krabbe disease, a rare genetic leukodystrophy. Diagnosis was
this interesting case ... Diagnosis was made ... leukodystrophy w/ deficiency ... neurotoxic • Symptoms ... #Diagnosis #MRI
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... Case description ... - **MSK rads ... diffuse chondral disease ... #msk #rheumatology
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
- Differential Diagnosis ... Leg Pain: • Fracture ... Legg-Calve-Perthes disease ... Vit B12, B6, Cu deficiency ... lower #extremity #msk
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Cellular immune deficiency ... Drugs, Unknown cause ... #management #treatment ... #summary #rheumatology