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classification differential disease erythematosus hematology signs sle symptoms systemic algorithm ana antibodies antinuclear antiphospholipid apls behcet behcets criteria cryofibrinogenemia cryoglobulinemia
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... Labs/Diagnosis: ... (e.g. systemic lupus ... Cryoglobulins #diagnosis ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... inflammation Others: • Lupus ... Thrombosis and arterial ... such as systemic lupus ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... signs #symptoms #diagnosis ... #rheumatology
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
- Diagnosis Diagnostic ... Uveitis or retinal vasculitis ... test Most Common Clinical ... venous thromboses, arterial ... #criteria #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Clinical Features ... #Rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
microscopy and serial ... likely it will be clinically ... SLE), Sjogren's Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... association • M > F Clinical ... Vascular Disease: Arterial ... (Clinical Dx). ... signs #symptoms #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... Cryofibrinogenemia Clinical ... : • + Clinical ... Antiphospholipid syndrome ... #rheumatology #
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
- 1 or more clinical ... episodes of arterial ... excluded Testing: • Lupus ... Workup #Algorithm #diagnosis ... #hematology
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