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diagnosis lupus signs syndrome vasculitis activation ana antibodies antinuclear autoantibodies behcet classification compared dermatology disease druginduced erythemas macrophage mas mimickers
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... #lupus #Systemic ... #Summary #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Photosensitivity, Butterfly rash ... #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... 69% - Malar rash ... #Erythematosus ... autoantibodies #signs #symptoms ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... rash • Erythematous ... Joint pain • Swan neck ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... months to years) Systemic ... Lupus Erythematosus ... #comparison #table ... #rheumatology #
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... (SLE), Systemic ... ANA #patterns #rheumatology ... #diagnosis #differential
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... Petechial or purpuric rash ... [SLE], AOSD) • ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
(cutaneous or systemic ... patches on the face, neck ... presenting with erythematous ... PrathitKulkarni #Erythemas #comparison ... #table #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... lupus erythematosus ... Symptoms (Sx) in ... vasculitis, and SLE ... #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... Behcet disease) Differential ... Oral aphthae : SLE ... Syndrome #diagnosis #management ... #rheumatology #
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