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diagnosis monoclonal activation anemia aplastic apml classification common cvid dermatologic eosinophilia eosinophils gammopathy granulomatosis hes hodgkins hypereosinophilia hypogammaglobulinemia immunodeficiency immunology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Sarcoidosis • GPA ... Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology ... #skin #rashes #differential ... #diagnosis #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... reticularis Differential ... • Goodpasture syndrome ... #dermatology #rash ... #diagnosis #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation ... Syndrome in APML ... initiation • Differential ... #diagnosis #management ... #hematology #oncology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... capillary leak syndrome ... • Schnitzler syndrome ... #Diagnosis #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... Pseudohyponatremia • ↓anion gap ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
impaired B-cell differentiation ... to 8 years Clinical ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... Petechial or purpuric rash ... #Diagnosis #Management ... #Hematology #Rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... Diagnosis and Management ... than 1500 and clinical ... eosinophilia #diagnosis #hematology ... #differential #
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
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