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diagnosis management differential oncology dermatology signs symptoms treatment erythematosus lupus sle systemic vasculitis workup algorithm anemia classification eosinophilia immunology leukemia
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Non-lmmune: • HELLP Syndrome ... Vasculitis • Infection ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... Extravascular #Causes ... differential #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... Thrombocytosis): • Acute infection ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... #hematology #secondary
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Framework Non-Infectious ... arteritis, Cogan's Syndrome ... (SPA) • Other Causes ... ), Idiopathic Infectious ... Differential #Diagnosis #rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... drug reaction, infection ... organ-specific signs ... or symptoms (eg ... Differential #diagnosis #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Diagnosis Neonate: - Infection ... Constitutional disorders, eg ... neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
39 C this is a clinical ... maintained fever CAUSES ... hyperthermia crisis (late ... sign) (→ 3-8) ... #Differential #Causes
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... WBC >100k, + lab signs ... proliferation rate ... unless worrisome EKG ... diagnosis #management #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
., HIV), EBV infection ... Autoimmune diseases • Clinical ... hepatosplenomegaly (Rare ... Etiology: - Infections ... #differential #hematology
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