54 results
Systemic Sclerosis (Scleroderma)
Limited - CREST:
 • Calcinosis
 • Raynaud phenomenon
 • Esophageal dysmotility
 • Sclerodactyly
 •
Systemic Sclerosis ... Calcinosis • Raynaud ... @AnnKumfer #Systemic ... Scleroderma #diagnosis #signs ... #symptoms #rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
and Symptoms: ... • Vascular: Raynaud's ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #workup
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
defect (rare) Raynaud's ... of hip (rare), Arthritis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Manifestations of Systemic ... Erythematosus (SLE) #Systemic ... Manifestations #Signs ... #Symptoms #Rheumatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
SLE) - Typical Signs ... /Symptoms Alopecia ... Lupus enteritis, Raynaud's ... , Arthralgia / arthritis ... #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
• Homogeneous: Systemic ... Juvenile Idiopathic Arthritis ... ) • Speckled: Systemic ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology
Cutaneous and Systemic Findings in Dermatomyositis
Cutaneous Findings:
 - Heliotrope sign and edema
 - Nail-fold changes
 -
Cutaneous and Systemic ... Gottron's papules - Raynaud's ... Systemic Findings ... #Cutaneous #Systemic ... Dermatomyositis #Diagnosis #Rheumatology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
Discoid Rash A Antinuclear ... cytopenias) A Arthritis ... IMDAMNSHARP #sle #systemic ... erythematosus #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... Juvenile Idiopathic Arthritis ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Anti-UI-ribonucleoprotein - 35% • Raynaud ... • MCTD (SLE/systemic ... Summary #diagnosis #rheumatology