19 results
diagnosis hematology systemic lupus sle treatment differential erythematosus hemophagocytic hlh lymphohistiocytosis oncology sclerosis summary syndrome ana antibodies arthritis autoantibodies autoimmune
Systemic Sclerosis (Scleroderma) Limited - CREST: • Calcinosis • Raynaud phenomenon • Esophageal dysmotility • Sclerodactyly •
Systemic Sclerosis (Scleroderma ... Calcinosis • Raynaud ... 10% - 15% • Scleroderma ... #diagnosis #signs ... #symptoms #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune disease ... and Symptoms: ... • Vascular: Raynaud's ... #SSc #rheumatology ... #workup
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... systemic sclerosis/scleroderma ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Erythematosus - Summary Antinuclear ... with more severe disease ... Anti-UI-ribonucleoprotein - 35% • Raynaud ... Summary #diagnosis #rheumatology ... #management
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
defect (rare) Raynaud's ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Photosensitivity 29% - Raynaud's ... sclerosis, Still's disease ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... autoantibodies (antinuclear ... #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis - Signs ... and Symptoms • ... Rheumatoid vasculitis, Raynaud's ... Arthritis #RA #Signs ... #rheumatology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Diagnosis and Management ... , signs, and complications ... von Willebrand disease ... PV #Diagnosis #Management ... Summary #treatment #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Syndrome Systemic disease ... meningitis), MCC CNS symptoms ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
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