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T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
- Persistent (>6mo) lymphocytosis (2-20k) with proven clonality

- Positive: CD2 ... , CD3, CD8 - Loss ... of CD5 and/or CD7 ... Rarely can be CD4

The Cell Cycle
The cell cycle is the series of tightly regulated steps that controls cell growth

Cyclin-dependent kinases (CDKs ... Retinoblastoma (Rb ... Both Rb and p53 ... in the case of Rb ... Cyclin-dependent kinase #CDK

COVID-19 Life Cycle

#COVID19 #LifeCycle #Timeline #Pathophysiology #Diagnosis

Cycle #COVID19 #LifeCycle

Lung Nodules - Differential Diagnosis by Distribution
• Centrilobular: Hypersensitivity Pneumonitis, RB-ILD, Pneumoconiosis, Infectious Bronchiolitis, Vasculitis,

Hypersensitivity Pneumonitis, RB-ILD

Upper lung zone preference is seen in:
- Inhaled particles: pneumoconiosis (silica or coal)
- Smoking related diseases

bronchiolitis (RB-ILD

Blood Disorders - Markers and Differential Diagnosis Algorithm
Acute
• Myloid (AML) - CD13, CD33, CD34,

- T-cell - CD7 ... , CD3 Chronic ... - B-cell CD5

Leishmaniasis Life Cycle
1) Sandfly takes a blood meal (injects promastigote stage into the skin)
Human Stages:
2) Promastigotes

Leishmaniasis #LifeCycle ... infectiousdiseases #cdc

Guide to Acute Kidney Injury (AKI)

What to ask/look for:
- HPI, PMH, full ROS

- Hx of AKI/CKD ... US w/ PVR - CPK ... 21% - AKI on CKD

Echinococcus Life Cycle
1) Adult in small intestine eggs
2) Embryonated egg in feces
3) Oncosphere hatches; penetrates intestinal

#Echinococcus #LifeCycle ... infectiousdiseases #cdc

Strongyloides fuelleborni Lifecycle
Free-Living Cycle
1) Eggs containing rhabditiform larvae passed in feces.
2) Rhabditiform larvae hatch in environment.

Strongyloides fuelleborni Lifecycle ... #fuelleborni #LifeCycle ... infectiousdiseases #cdc

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