12 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... CNS Opportunistic ... • CNS opportunistic ... and <25% culture positive ... #differential #
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... , Coxsackie, CMV ... Muscular: normal CK ... Disease #diagnosis #management ... #treatment #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... pleural effusions, CNS ... keratitis, iritis • CMV ... #Differential # ... Diagnosis #Management
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... parainfluenza, Coxsackie, HIV ... , CMV, EBV - Bacterial ... Up: • Chem: CPK ... #Weakness #Differential
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
- Differential ... Coccidioidomycosis, CMV ... Pneumonia: • 3 syndromes ... high fever CMV ... Lymphadenopathy, CNS
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
basal ganglia, CNS ... Skin lesions • Positive ... Behcet disease) Differential ... #diagnosis #management ... signs #symptoms #rheumatology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Framework and Management ... Infection - Viral (HIV ... Myoglobinuria: UA positive ... #Diagnosis #Management
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
chemotherapy) • Genetic syndromes ... • Infections - HIV ... CMV. ... ICL #diagnosis #hematology ... #Differential #
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... initiation • Differential ... • Steroids: IV ... coagulopathy, RRT/IMV ... APML #diagnosis #management
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... (CAS): - Due ... dehydrogenase • Positive ... Mycoplasma, EBV, HIV ... younger pts) Differential