18 results
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Warm Antibody Autoimmune ... Hemolytic Anemia 1) DIAGNOSE ... • Blood smear: Differential ... #management #treatment ... #rheumatology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Diagnosis Framework ... Aplastic anemia, CKD ... - Extrinsic: Autoimmune ... Non-megaloblastic: Liver disease ... #Diagnosis #hematology
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Hypocalcemia - Diagnosis ... and Management ... (CKD) - Metabolism ... granuloma) - Autoimmune ... #differential #
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • ... Muscular: normal CK ... #diagnosis #management ... #treatment #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... Disorders, Infection, Autoimmune ... Thyroid, Autoimmune ... ANA #patterns #rheumatology ... #diagnosis #differential
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
in HIV / AIDS - Differential ... Diagnosis Framework ... Demyelinating disease ... and <25% culture positive ... CNS #Infections #differential
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... and Management ... thrombocythemia), Autoimmune ... disease • vWF ... #hematology #differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral infection, autoimmune ... dehydrogenase • Positive ... CLL (older) • Autoimmune ... pts) Differential ... hemolytic #anemia #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... solid cancers • Autoimmune ... diseases: SLE++ ... #management #treatment ... #summary #rheumatology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
and Management ... Hyperthyroidism - Autoimmune ... Myoglobinuria: UA positive ... of underlying disease ... #Diagnosis #Management