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Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
hypersensitivity reactions ... Allergen-specific lgE causes ... Acute transfusion reaction ... hypersensitivity #reactions ... classification #comparison
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
- Transfusion Reactions ... without other cause ... #Transfusion #Reactions ... hematology #diagnosis #comparison
Generalized Seizures and Pseudoseizures Generalized seizures "are conceptualized as originating as some point within, and rapidly engaging,
general seizure caused ... and metabolic causes ... to a conversion reaction ... Signs #Symptoms #Comparison
Shock - Differential Diagnosis Framework MAP = CO x SVR Hypovolemic (↓ Intravascular volume): • Hemorrhage, dehydration due
findings based on cause ... syndrome, infusion reactions ... Diagnosis #table #comparison
Hyperthermic Toxidromes Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures. • Sympathomimetic -
Ideosyncratic reaction ... pharmacogenetic disease caused ... Hyperthermic #Toxidromes #comparison
Eosinophils (Eos) and hypereosinophilia (HE) Caused by eosinophilopoietic cytokines Common causes: - Drug reaction - Helminth infection -
hypereosinophilia (HE) Caused ... cytokines Common causes ... : - Drug reaction ... infection - Allergic reaction ... disease Rare causes
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
during an allergic reaction ... Or Inflammatory Reactions ... Chickenpox Other Causes ... Differential #Diagnosis #causes
Symptoms Distinguishing Groups of Cutaneous Drug Reactions IgE-mediated reactions: • Onset minutes to hours into treatment course
Cutaneous Drug Reactions ... IgE-mediated reactions ... T-cell-mediated reactions ... T-cell-mediated reactions ... dermatology #clinical #comparison
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
and Extrinsic Causes ... autoimmune (most of the causes ... hemolytic transfusion reactions ... Differential #Diagnosis #Causes
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
blisters, possibly crusts ... Bullous impetigo - Reaction ... diabeticorum) - Reaction ... Diagnosis #Algorithm #causes
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