27 results
Iron Deficiency in Congestive Heart Failure (CHF)

Iron deficiency (ID) in heart failure is a common comorbidity
Heart Failure (CHF ... 50% of patients, leading ... depot iron] Treatment ... #pharmacology # ... pathophysiology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
decompensation (CHF ... hyperparathyroidism Treatment ... • Slow initial feeding ... initiation of feeding ... Differential #Diagnosis #Pathophysiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 33% • Treatment ... : Age>60, CKD, CHF ... : No • Treatment ... hematology #diagnosis #comparison
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Differential Diagnosis: Infection ... sepsis), PE, DAH, CHF ... management #hematology #oncology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... DOACs thereby leading ... metabolization leading ... #Chemotherapy #Oncology ... Interactions #Table #Pharmacology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
temporal evolution, CSF ... Antimicrobial treatment ... hemorrhage • CSF ... visual changes, hearing ... comparable to CSF
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... involvement - seeding ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... response preceding infection ... - NORMAL CSF ... Treatment: • Plasmapheresis ... diagnosis #management #treatment
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
to a preceding infection ... • Most common infection ... jejuni • Other infections ... the underlying pathophysiology ... and cauda equina TREATMENT
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... involvement - seeding ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment