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diagnosis table apml cardiology chemotherapy cyp3a4 deficiency differentiation doac failure heart inducers inhibitors interactions iron management mds myelodysplasia myelodysplastic pglycoprotein
Iron Deficiency in Congestive Heart Failure (CHF) Iron deficiency (ID) in heart failure is a common comorbidity
Heart Failure (CHF ... 50% of patients, leading ... depot iron] Treatment ... #pharmacology # ... pathophysiology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
: 33% • Treatment ... : Age>60, CKD, CHF ... : No • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
interactions) Cancer-treatment ... DOACs thereby leading ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Pathophysiology ... Differential Diagnosis: Infection ... sepsis), PE, DAH, CHF ... diagnosis #management #hematology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... • Parvovirus infection ... factors (examples: G-CSF ... Syndromes #diagnosis #hematology ... #oncology
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