11 results
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Class Overview ... Rapidly cidal drug ... gram negative activity ... skin/soft tissue infections ... cidal nature) #Pharmacology
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
Class Overview ... positive agent with activity ... Drug of choice for ... #Pharmacology #Antibiotics ... #Review #Overview
Antibiotic classification refers to the categorization of antibiotics based on their chemical structure, mechanism of action,
and spectrum of activity ... drugs that are used ... treat bacterial infections ... Imagine treatments ... #Antibiotics #pharmacology
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Echinocandins - Antibiotics ... Class Overview ... vs Candida -> Drug ... Echinocandins lack activity ... Anidulafungin #Pharmacology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... drug use • Silicosis ... involvement - seeding ... Tuberculosis Treatment ... Initiating Treatment
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Class Overview ... other agents are: activity ... including PCP PNA (drug ... choice, both for treatment ... #Pharmacology #Antibiotics
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... drug use • Silicosis ... involvement - seeding ... Tuberculosis Treatment ... Initiating Treatment
Tetracyclines – Doxycycline, Tetracycline, Minocycline - Antibiotics Class Overview

- 30S Inhibitors (PO and IV)
Spectrum: Fairly broad
Minocycline - Antibiotics ... Class Overview ... Has activity for ... Drug of choice for ... #Pharmacology #Antibiotics
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
IDSA Recommendations ... Tuberculosis Infection ... no evidence of active ... Tuberculosis #TB #IDSA ... #HIVAIDS #pharmacology
Anti-Pseudomonal - Antibiotics Class Overview

Pseudomonas aeruginosa is a non-fermenting Gram-negative bacillus that inhabits a variety of
Class Overview ... Ertapenem has no activity ... empiric Pseudomonas treatment ... Polymyxin B(IV) #Pharmacology ... #Overview #AntiPseudomonal