11 results
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Rapidly cidal drug ... gram negative activity ... skin/soft tissue infections ... cidal nature) #Pharmacology ... #Antibiotics #Review
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
Antibiotics Class Overview ... positive agent with activity ... Drug of choice for ... #Pharmacology #Antibiotics ... #Review #Overview
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Antibiotics Class Overview ... vs Candida -> Drug ... Echinocandins lack activity ... Anidulafungin #Pharmacology ... #Antibiotics #Review
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... drug use • Silicosis ... involvement - seeding ... Tuberculosis Diagnosis ... Tuberculosis #TB #Diagnosis
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... drug use • Silicosis ... involvement - seeding ... Tuberculosis Diagnosis ... Tuberculosis #TB #Diagnosis
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
other agents are: activity ... including PCP PNA (drug ... choice, both for treatment ... #Pharmacology #Antibiotics ... #Review #Overview
Antibiotic classification refers to the categorization of antibiotics based on their chemical structure, mechanism of action,
and spectrum of activity ... Antibiotics are drugs ... treat bacterial infections ... Imagine treatments ... #Antibiotics #pharmacology
Tetracyclines – Doxycycline, Tetracycline, Minocycline - Antibiotics Class Overview

- 30S Inhibitors (PO and IV)
Spectrum: Fairly broad
Antibiotics Class Overview ... Has activity for ... Drug of choice for ... #Pharmacology #Antibiotics ... #Review #Overview
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome - Overview ... superinfection, drug ... : • Drug reaction ... • Persistently active ... infection/drug
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
no evidence of active ... for active or latent ... Active TB Disease ... and molecular diagnostic ... #HIVAIDS #pharmacology