18 results
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Antibiotics Class Overview ... Rapidly cidal drug ... gram negative activity ... skin/soft tissue infections ... cidal nature) #Pharmacology
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Antibiotic Failure - Differential ... Immunocompromise Treatment ... ocular), Tissue activity ... • Secondary to Treatment ... Antibiotic #Failure #Differential
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
Antibiotics Class Overview ... positive agent with activity ... Drug of choice for ... #Pharmacology #Antibiotics ... #Review #Overview
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... drug use • Silicosis ... involvement - seeding ... Tuberculosis Treatment ... Initiating Treatment
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Antibiotics Class Overview ... vs Candida -> Drug ... severe Candida infections ... Echinocandins lack activity ... Anidulafungin #Pharmacology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... drug use • Silicosis ... involvement - seeding ... Tuberculosis Treatment ... Initiating Treatment
Antibiotic classification refers to the categorization of antibiotics based on their chemical structure, mechanism of action,
and spectrum of activity ... Antibiotics are drugs ... treat bacterial infections ... Imagine treatments ... #Antibiotics #pharmacology
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Antibiotics Class Overview ... other agents are: activity ... including PCP PNA (drug ... choice, both for treatment ... #Pharmacology #Antibiotics
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis Overview ... life-threatening Differential ... - Symptomatic Treatment ... precipitated by: Drugs ... , infection, surgery
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome - Overview ... Leishmaniasis Differential ... • Persistently active ... infection/drug ... Inflammatory #Syndrome #Differential