14 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Clotmaster #VTE #DOAC ... Rivaroxaban #Edoxaban #Loading ... #DVT #Pharmacology ... #Hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
) Cancer-treatment ... thereby leading ... metabolization leading ... Chemotherapy #Oncology #Hematology ... Interactions #Table #Pharmacology
Conversion - Epoetin alfa (Procrit®) to Darbepoetin alfa (Aranesp™)

#Epoetin #Darbepoetin #Erythropoietin #Conversion #Table #ESAs #Procrit #Aranesp
Procrit #Aranesp #Pharmacology ... #Hematology #Nephrology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... anticoagulant treatment ... not available #DOAC ... anticoagulant #hematology ... #management #pharmacology
Migraine - Preventative Treatments

 • Anticonvulsants: *Topiramate, *Sodium valproate, Gabapentin, Pregabalin
 • Antidepressants: Amitriptyline, Venlafaxine, Duloxetine,
- Preventative Treatments ... #Preventative #Treatment ... #prophylaxis #prevention ... #pharmacology # ... neurology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
OR NON-WEIGHT BEARING ... upset, non weight bearing ... splenomegaly, abnormal neurology ... , back pain Haematology ... cell disease Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
inflammation, leading ... Puncture, EEG Treatment ... APS), Secondary prevention ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
Treatment includes ... prevention by minimizing ... Vancomycin #AKI #pharmacology ... diagnosis #management #nephrology
Triptan Selection - Migraine Management
Choosing triptans:
 • Reponse to given triptan do not predict to others
response: • Consider preventive ... Migraine #Management #treatment ... #neurology #pharmacology ... selection #headache #neurology
Complications after Bariatric Surgery
Post Bariatric Intestinal Failure:
 • Severe protein malnutrition after bariatric surgery
 • More
nutrients • TPN for treatment ... inuslin release leading ... excluded limb • Treatment ... and prevention ... Gastroenterology and Hepatology