23 results
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential ... of breath • Neurologic ... Hyperuricemia • Acute renal ... Vomiting, decreased urine ... #differential #
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Hyponatremia - Differential ... Pain/Post-op • Neurologic ... Malignancy True hypovolemia ... GI losses • Renal ... Hypo-osmolar urine
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Hyponatremia - Differential ... Pain/Post-op • Neurologic ... Malignancy True hypovolemia ... GI losses • Renal ... Hypo-osmolar urine
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
associated with hypokalemia ... overdose) - Sodium ... Fanconi syndrome ... #Medications #differential ... #diagnosis #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
A urine K/Cr ratio ... suggests extra-renal ... • Diarrhea A urine ... diagnosis #Algorithm #differential ... #potassium #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... (renal potassium ... Hypocalciuria (spot urine ... ratio 0.5%) Differential ... Rhabdomyolysis Treatment
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - Differential ... Algorithm 1) Check Urine ... mOsm/kg - Implies renal ... , Cushing syndrome ... #sodium
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Weakness - Dark urine ... hour with goal urine ... Rhabdomyolysis #Differential ... #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
volume-based algorithm Urine ... Present (Uosm ≥100): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... #Hyponatremia #differential ... #nephrology
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing
Common causes: 
 • Renal parenchymal disease
Hypertension - Differential ... (correction of hypokalemia ... Oral sodium loading ... test (with 24-h urine ... • Cushing’s syndrome