205 results
Central Nervous System Pharmacology - Somatic and Autonomic Receptors
Somatic
 • Rocuronium -> Non-depolarizing (reversible competitive inhibitors)
and Autonomic Receptors ... Ach -> Nicotinic Receptor ... -> Muscarinic Receptor ... -> Adrenergic Receptor ... -> Adrenergic Receptor
Third Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) Example: Aripiprazole
Dopamine D2 Receptor Partial Agonist
 • Binds
Binds to the D2 receptor ... bind to the D2 receptor ... over-stimulating receptors ... Bind to 5-HT 1A receptor ... similar to D2-receptor
Action potential
a, adrenergic receptor
Heart, glands, smooth muscle
Inactivated:
by #MAO
by #COMT
Capillary
Diffusion into blood (raises NE in blood)
Activates
Inhibits
Adrenal medulla
#L-tyrosine
Varicosities
Epinephrine
Bloodstream
Inactivated
a, adrenergic receptor ... B2 adrenergic receptor ... a, adrenergic receptor ... Epinephrine #adrenergic receptors ... 02 #adrenergic receptors
Receptor actions of sympathomimetic and dopaminergic agents.
Adrenaline (epinephrine) 
Noradrenaline (norepinephrine) 
Isoprenaline 
Dopamine 
Dopexamine 
Dobutamine 

#Pharmacology #Vasopressors
Receptor actions ... #Vasopressors #Receptors
Vasoactive Agents - Receptor Profiles
Adrenergic Profile: α → β
phenylephrine, norepinephrine, dopamine, epinephrine, dobutamine, isoproterenol

- Dr. Rishi
Vasoactive Agents - Receptor ... Vasoactive #Agents #Receptors
Summary of the therapeutic uses of adrenergic agonists
Table of Catecholamine Pressors, Non-Catecholamines, Alpha and Beta Receptor
Alpha and Beta Receptor ... NonCatecholamines #Receptors
Second Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
Note: Receptor binding ... • Dopamine D2 Receptor ... • Serotonin 2A Receptor ... -HT on 5-HT 2A receptors ... • Serotonin 2C Receptor
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
specific GABAA receptor ... specific GABA-A receptor ... subgroup of GABAA receptors ... duration 5-HT-Receptor ... agonist at 5-HT receptors
Vasopressor Receptor Activities
alpha - beta1 - beta2 - DA - Vasopressin
Dopamine (ug/kg/min)
Epinephrine (ug/kg/min)
Norepinqhrine (ug/min)
Phenylephrine (ug/min)
Vasopressin (units/min)

#Vasopressors
Vasopressor Receptor ... #Vasopressors #Receptors
Angiotensin-Converting Enzyme Inhibitors - Inhibit the conversion of AngI to AngII
 • Captopril, Lisinopril, Enalapril, Benazepril,
Perindopril Angiotensin Receptor ... Blockers - Block AT1 receptors