23 results
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
constipation • Allergic reaction ... mediated cytotoxic reaction ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
AACE/ACE 2016 Postmenopausal Osteoporosis Treatment Algorithm

Evaluate for causes of secondary osteoporosis

Correct calcium/vitamin D deficiency and address
Evaluate for causes ... deficiency and address causes ... • Recommend pharmacologic ... therapy • Education ... Postmenopausal #Treatment
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Decr ROM in hip abduction ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... signs #diagnosis #msk
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... Puncture, EEG Treatment ... Lupus Cerebritis Induction ... diagnosis #management #treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
on: - ongoing production ... injury in the production ... / hypoxemia -> focus ... perfusion - shock->treatments ... before beginning treatment
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... coagulation factors - Reduction ... + Bleeding Treatment ... Treat primary cause ... #treatment #management
Neurological Side Effects of Antipsychotic Drugs
Acute dystonia - Spasm of muscles of tongue, face, neck, back
variable tremor, mask ... risk • Tx: Dose reduction ... months or years of treatment ... months or years of treatment ... #SideEffects #pharmacology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... blood cells + production ... Drugs, Unknown cause ... Treatment: • ... diagnosis #management #treatment
An Algorithm for the Management of Seizures

The management of active seizures is algorithmic, starting with a
and bag-valve mask ... Pharmacologic treatment ... The focus is on
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
& Dry) is the treatment ... from LV afterload reduction ... and afterload reduction ... the determined cause ... icu #clinical #pharmacology