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diagnosis hematology bruising algorithm intravascular prolonged pt anemia disseminated hemolysis hemorrhage hemostasis management obgyn obstetrics pediatrics peds postpartum pph purpura
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... coagulation (DIC ... #Hemolytic #Intravascular ... #Extravascular ... #Causes #differential
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Coagulation (DIC ... Treat primary cause ... INR < 2.3 - APTT ... #causes #treatment
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Disseminated intravascular ... coagulation (DIC ... Jcortesizaguirr #Abnormal ... #differential #
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Destruction • Abnormal ... Rare • Drugs (e.g ... #Differential #
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... intravascularcoagulation (DIC ... amyloidosis #Abnormal ... #differential # ... hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... /NORMAL PTT: Suggests ... ABNORMAL PTT: Prolongation ... discern these causes
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... Hemorrhage - Differential ... succenturiate lobe • Abnormal ... coagulation (DIC ... ) • Anti-coagulation
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... purpura - DIC ... coagulation) ... Platelet count normal ... pediatrics #diagnosis #differential
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