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differential coagulation hemolytic abnormal algorithm aptt bruising hemolysis bleeding classification disseminated hemorrhage hemostasis maha management microangiopathic microscopy obgyn obstetrics pathology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
vs Extravascular ... Causes Intravascular ... coagulation (DIC ... #Extravascular ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... and Intravascular ... Algorithm Extravascular ... • MAHA (TTP, DIC ... #Hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Disseminated intravascular ... coagulation (DIC ... #Causes #diagnosis ... #differential #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... IVIG infusion Intravascular ... : TTP, HUS, DIC, ... #hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... and laboratory diagnosis ... as disseminated intravascular ... count, D-dimer, egg ... #Hematology #Pathology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Thrombocytopenia • Prolonged ... #Disseminated #Intravascular ... #Coagulation #diagnosis ... #management #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... for a Prolonged ... intravascularcoagulation (DIC ... #Causes #diagnosis ... #differential #hematology
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... - Differential Diagnosis ... . prolonged/induced ... • Disseminated intravascular ... coagulation (DIC
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
be performed PT ... result in severe anemia ... reflection of intravascular ... immune hemolytic anemia ... #Workup #Hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... prolonged after ... , disseminated intravascular ... discern these causes ... #Hematology
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