9 results
Oral anti-hypertensives with relative fast onset of action (Hypertensive Emergency)

The key concern with oral antihypertensive agents
fast onset of action ... concern with oral antihypertensive ... up-titrating medications (e.g ... #Oral #antihypertensives ... #Pharmacology #Table
Visual Guide to AV Nodal Reentrant Tachycardia (AVNRT) - Pathophysiology
 - Dual AV nodal physiology is
Visual Guide to AV ... Nodal Reentrant ... Tachycardia (AVNRT) - Pathophysiology ... ECG usually shows ... Tachycardia #AVNRT #Pathophysiology
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
Contraindications to Antihypertensive ... diltiazem) - AV ... Pgp-dependent drugs (e.g ... Xerostomia #antihypertensive ... contraindications #table
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
Immune Reactions ... cytokine synthesis, e.g ... #Pharmacology #Pathophysiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... blood donor • Pathophysiology ... transfusion • Pathophysiology ... #Transfusion #Reactions ... diagnosis #comparison #table
Bone resorption and the relationship between osteoblasts and osteoclasts.  
RANK is expressed on the osteoclasts,
linking proteins (e.g ... , wherein reactions ... Several acids (e.g ... released through the actions ... #Pathophysiology
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
Adrenoceptor Actions ... • Heart - ↑ AV ... adrenergic #receptors #actions ... #pharmacology #pathophysiology ... #comparison #table
Anaphylaxis: Treatments (Acute)
Additional Info:
 • IV steroids may be considered for prevention of late phase reactions.
of late phase reactions ... antagonist use (e.g ... adjunct therapy) e.g ... adjunct therapy) e.g ... Treatments #Management #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Classification #Pathophysiology ... Allergy #Diagnosis #Reactions ... #Table