54 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... - Soft tissue expansion ... #FeedbackLoop #endocrinology ... #pathophysiology
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... Immobilization Hypercalcemia ... #Causes #differential ... calcium #high #endocrinology
Causes of Hypercalcemia

#Differential #Hypercalcemia #Diagnosis #Causes #Endocrinology
Causes of Hypercalcemia ... #Differential #Hypercalcemia ... #Diagnosis #Causes ... #Endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... GH excess prior ... • Other rare causes ... signs #symptoms #endocrinology ... #pathophysiology
Causes of Hypercalcemia - Differential Diagnosis Algorithm
 • Primary Hyperparathyroidism 
 • Possible Familial Hypocalciuric Hypercalcemia
Causes of Hypercalcemia ... Hypocalciuric Hypercalcemia ... • Humoral Hypercalcemia ... Diagnosis #Algorithm #Causes ... #endocrinology
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... other hormonal causes ... for non-hormonal causes ... uw_IMresidency #Hypercalcemia ... Diagnosis #algorithm #endocrinology
Hypocalcemia - Workup Algorithm

Dr Nikhil Lohiya - NEPHKIDS 2020 @NEPHKIDS1

#Hypocalcemia #Workup #Algorithm #differential #diagnosis #endocrinology #causes
Hypocalcemia - Workup ... @NEPHKIDS1 #Hypocalcemia ... differential #diagnosis #endocrinology ... #causes #calcium
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... growth hormone (GH ... Symptoms #Diagnosis #Endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... • GH stimulates ... or refractory cases ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Hypercalcemia - ... Hypocalciuric Hypercalcemia ... Thiazides/Lithium #Hypercalcemia ... Diagnosis #Algorithm #causes ... #endocrinology