13 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
(TLS) and Treatment ... Abnormalities of TLS ... Laboratory TLS ... Calcium ≤ 7.0 mg/dL Clinical ... #management #oncology
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... Treatment of Clinical ... TLS: • IV fluids ... MatthewHoMD #TLS ... #oncology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... but can also spontaneously ... #Tumor #Lysis #Syndrome ... #TLS #oncology ... #management #UricAcid
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Motor Nerves: ALS ... Guillain-Barre syndrome ... heavy metals), Critical ... Lambert Eaton Syndrome ... Weakness #Causes #differential
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
considered for urgent referral ... presence of metabolic syndrome ... repeat testing or referral ... result in urgent referral ... Liver #Enzymes #Differential
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... ) Summary ALS: combination ... (1) limb-onset ALS ... conditions listed in differential ... neurology #diagnosis #management
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Features: POEMS, AL ... capillary leak syndrome ... • Schnitzler syndrome ... Diagnosis #hematology #oncology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... life-threatening Differential ... Generalized fatigue - ALS ... Clinical DX: - ... Gravis #diagnosis #management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Framework and Management ... HIV, Influenza, TSS ... Dermatomyositis Clinical ... #Diagnosis #Management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... initiation • Differential ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology