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diagnosis management hematology syndrome differential rheumatology algorithm neurology cirrhosis encephalopathy hemophagocytic lymphohistiocytosis oncology reactions biliary blood classification endocrinology gastroenterology hepatic
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
) Treatment Primary ... or autoimmune disease ... transplantation for refractory ... disease - Dr. ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... • Autoimmune diseases ... Adult-onset Still disease ... Treatment: • ... diagnosis #management #treatment
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... Anticoagulation (case ... by case) • Surgery ... #Syndrome #Treatment
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
female-predominant disease ... Risk Factors: HLA ... variants, Non-HLA ... of autoimmune disease ... #hepatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... age, however the disease ... • Bicytopenia Treatment ... diagnosis #management #treatment ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... PT, aPTT(liver disease ... bypass), LFT (liver disease ... Refractory ITP, ... #Workup #hematology
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
vasculitis - Diagnosis, causes ... neuropathy Treatment ... remission - Refractory ... associated with refractory ... disease Dr.
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... highly inflammatory disease ... hypersensitivity syndromes • HLH ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... disorders • Celiac disease ... effect following treatment ... Diagnosis #Algorithm #Causes ... #Hematology
Hyponatremia - Diagnosis and Treatment Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia is usually caused ... Treatment: Treatment ... the underlying cause ... options for severe/refractory ... vaptans (HF/liver disease
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