13 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... • Autoimmune diseases ... Adult-onset Still disease ... Unknown cause Treatment ... diagnosis #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
) Treatment Primary ... or autoimmune disease ... , treatment of underlying ... transplantation for refractory ... disease - Dr.
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Syndrome Systemic disease ... common in Asia • HLA-B51 ... ) Differential Diagnosis ... Arthritis, AS Treatment ... azathioprine • Severe or refractory
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
approach to the differential ... Treatment: Treatment ... options for severe/refractory ... vaptans (HF/liver disease ... #Hyponatremia #Differential
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... hemorrhage • Treatment ... several months of treatment ... Lung Abscess Differential ... Abscess #pulmonary #differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... initiation • Differential ... Renal Failure Treatment ... dysfuxtion, ICU, refractory
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Differential Diagnosis ... adenoma, ↓(TFT, LH ... Radiotherapy: Relapse or refractory ... Endocrinology #Treatment ... #Pathophysiology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's lymphoma (HL ... rich classical HL ... Immunohistochemical studies (to differentiate ... number of sites of disease ... Hodgkin Lymphoma Treatment
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
due to chronic disease ... hyperparathyroidism Treatment ... Syndrome #Nutrition #Differential ... #Diagnosis #Pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Shock, Autoimmune disease ... Etiology: • Pathophysiology ... Reversible course Differential ... epilepticus Treatment ... underlying cause • Treatment