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diagnosis differential algorithm hematology causes management clinical pathophysiology symptoms signs workup treatment hemolytic neurology pharmacology cardiology nephrology classification deficiency pediatrics
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... Algorithm • Relapse ... #Aplastic #Anemia
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic Anemia ... severe disease If relapse ... Autoimmune #Hemolytic #Anemia
Treatment of giant cell arteritis (GCA) 1st Line Strategy - GC 0.7 mg/kg/day, except for: • Aortitis
necrosis, stroke) Relapses ... • 1st relapse: Incr ... mg/jd • 2nd relapse ... vice-versa • >2 relapses ... Treatment #Management #Relapses
Differential Diagnosis of Anemias #Diagnosis #IM #Honc #Anemia #Differential #Iron #Algorithm #Microcytic #Macrocytic #Normocytic #Ddxof
Differential Diagnosis of Anemias ... Diagnosis #IM #Honc #Anemia
Multiple Myeloma - Management Algorithms - Treatment Initiation - Frontline Treatment - First Relapse - Second
Treatment - First Relapse ... Second or Higher Relapse ... oncology #treatment #relapse
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Algorithm Signs of anemia ... Autoimmune Hemolytic Anemias ... Alloimmune Hemolytic Anemias ... #Hemolytic #Anemias
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... Chronic disease anemia ... Sideroblastic anemia ... iron deficiency anemia ... Autoimmune hemolytic anemia
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
breakdown • Anaemia ... Hemolysis #Hemolytic #Anemia
Dacrocytes (tear drop cells) Other poikilocytes resemble a pear or teardrop. The narrow, tapered end may be
metaplasia, pernicious anemia ... some hemolytic anemias
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Iron-deficiency anemia ... Sideroblastic anemia ... Megaloblastic anemia ... Sideroblastic anemia ... , Pernicious anemia
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