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differential pain erythematosus systemic workup activation ana antibodies antimda5 antinuclear approach classification conditions disease extrarticular laboratory macrophage mas msk oncology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
rheumaticum • Rheumatic ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #differential #diagnosis ... #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
, SLE, Rheumatic ... , Reactive arthritis ... • Bloody or ... #differential #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... , Polymyositis/Dermatomyositis ... : Lupus (SLE), Systemic ... ANA #patterns #rheumatology ... #diagnosis #differential
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... bacterial), acute rheumatic ... spondyloarthropathies, lupus ... Chronic = RA, SLE ... #rheumatology #
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
interphalangeal joints ... onset [33-74%] • Blood ... #AntiMDA5 #Dermatomyositis ... #rheumatology # ... dermatology #diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of hip (rare), Arthritis ... Demyelinating syndromes ... signs #symptoms #diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... ANCA-associated vasculitis, rheumatoid ... Still disease, dermatomyositis ... #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... • Systemic lupus ... of reactive arthritis ... ANA and RF (if clinical ... #testing #Rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
skin lesions + Rheumatic ... • A clinical diagnosis ... #Rheumatology # ... diagnosis #management ... #Dermatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
, breast CA - Hematologic ... - Neutrophilic rheumatoid ... - Lupus - Leukemia ... neutrophils in the blood ... #diagnosis #dermatology
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