1216 results
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
and apixaban are reported ... and apixaban are reported ... edoxaban has been reported ... Interactions #Table #Pharmacology
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Also, rare reports ... Anidulafungin #Pharmacology
Characteristic features of fluoroquinolone-induced tendinopathy/tendon rupture

Causative quinolones reported, Associated risk factors, Relative risk of tendon disorders,
Causative quinolones reported ... Risks #Factors #Pharmacology
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19

IL-6 activates T cells and macrophages, among other cell types (see
IL-6 levels are reported ... Siltuximab #COVID19 #Pharmacology
Antiplatelet Conversion - Switching Between P2Y12 Inhibitors
Oral P2Y12 inhibitors vary in potency and pharmacokinetic and dynamic
(ACS) has been reported ... ticagrelor #prasugrel #pharmacology
Emergency Treatment Algorithm for Convulsive Status Epilepticus
1. ABCDEFG (ABC's and Don't Ever Forget the Glucose)
2. Airway:
IV, max 4 mg, repeat ... Management #Neurology #Pharmacology
Pharmaceutical agents other than olmesartan have been reported to cause villous atrophy on occasion and are
olmesartan have been reported ... #Pharmacology #Drugs
Rasburicase Pharmacology Summary

Recombinant urate oxidase from saccharomyces
Immediate onset of action
Dosing:
 - Package insert: 0.2 mg/kg IV
Rasburicase Pharmacology ... allantoin Monitoring: repeat ... #Rasburicase #Pharmacology
Naloxone - Toxicology

Adult starting dose:
 - 0.4 mg IV/IM/IO/SQ for non-opioid dependent patients
 - 0.04 mg
opioid-dependent patients Repeat ... Toxicology #Management #Pharmacology
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
with ~100 cases reported ... Benefits #Lupus #pharmacology