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Lung volumes and capacities. Representation of a simple spirogram and divisions of lung volumes and capacities.

Capacities #Reserve #Residual ... #Tidal #TLC #IRV

Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
• Uric

Lysis Syndrome (TLS ... Abnormalities of TLS ... Laboratory TLS ... mg/dL Clinical TLS ... Treatment of TLS

Lung Volumes Diagram
• VC - Vital Capacity
• TLC - Total Lung Capacity
• RV

Vital Capacity • TLC ... Capacity • RV - Residual ... FRC - Functional Residual ... Lung #Volumes #TLC

Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,

lysis syndrome (TLS ... TumorLysis #syndrome #TLS

Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
• Purines -> Hypoxanthine /

Lysis Syndrome (TLS ... TumorLysis #Syndrome #TLS

H’s and T’s Mnemonic - Causes of Cardiac Arrest
H's - Hypovolemia, Hypoxia, Hydrogen Ions (acidosis), Hyperkalemia

H’s and T’s Mnemonic ... , Hypoglycemia T's ... , Trauma #Hs #Ts

Lung Volumes and Capacities

The amount of air that moves in and out of the lungs during

The residual volume ... The functional residual ... lung capacity (TLC

Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider

Treatment of Clinical TLS ... MatthewHoMD #TLS

Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of

#Presentation #TLS

Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
• Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity

leukapheresis - TLS ... Lysis #Syndrome #TLS

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