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diagnosis symptoms differential management disease erythematosus hematology lupus scleroderma sclerosis sle syndrome workup algorithm ana anca antibodies antibody antineutrophil antinuclear
Systemic Sclerosis (Scleroderma) Limited - CREST: • Calcinosis • Raynaud phenomenon • Esophageal dysmotility • Sclerodactyly •
Systemic Sclerosis ... • Scleroderma renal ... @AnnKumfer #Systemic ... Scleroderma #diagnosis #signs ... #symptoms #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... Butterfly rash, Vasculitis ... Abdominal pain (20%) Renal ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... arterial HTN) • Renal ... : scleroderma renal ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... central nervous system ... purpura: strong sign ... • Urinalysis (Renal ... differential #diagnosis #rheumatology
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 1) Suggestive clinical manifestations
Diagnosis of IgA Vasculitis ... - Most common systemic ... complications - Renal ... the skin - Systemic ... HSP #Diagnosis #Rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
antibodies) • Systemic ... drug-induced SLE) • Systemic ... ANCA-Associated Vasculitis ... vasculitis - MPO ... antibodies #diagnosis #rheumatology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
ASA) • Renal Disease ... Vascular System ... TeIangiectasia Vascular System ... • Steroids • Vasculitis ... Algorithm #Causes #Hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... Diagnosis: • Systemic ... Presentation: Systemic ... purpura: Strong sign ... Differential #Diagnosis #Rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
inflammatory vasculitis ... sx + signs/sx of ... differential diagnosis = vasculitis ... them, but urgent rheumatology ... GCA #Temporal #Signs
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
neuropathy) • Systemic ... Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular Vasculitis ... vascular beds-renal ... Paraproteinemias #Hematology
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