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diagnosis hematology management chronic hemeonc leukemia lymphocytic syndrome workup aids apml bandemia causes cbc classification cns differentiation fever hemophagocytic hiv
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... Lymphocytosis on CBC ... lymphoproliferative disorders ... diagnosis #workup #oncology ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... procedures - Infection ... (CVID, WAS), (neurologic ... not required in all ... #Differential #
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... -cell count more ... Suspect in movement disorders ... status, and focal neurologic ... #differential #
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... leukemia in adults • Disorder ... Complications: 1) Infection ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Left Shift: • Cell ... Neutrophil (Normal) Differential ... #Bandemia #differential ... neutrophil #WBC #CBC ... #hematology #pathophysiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... • Induce blast cell ... initiation • Differential ... Diagnosis: Infection ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... petechiae) • Frequent infections ... • Parvovirus infection ... blood count with differential ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... History of EBV infection ... • Autoimmune disorders ... Immunohistochemical studies (to differentiate ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Triggers: ▪ Infections ... Pathophysiology ... of NK cells and CD8 ... underlying trigger: Infections ... malignancy, autoimmune disorder
PFAPA Syndrome - Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis EPIDEMIOLOGY: PFAPA is the most common syndrome entailing
fever (FMF) PATHOPHYSIOLOGY ... DIFFERENTIAL DIAGNOSIS ... contributor to this disorder ... upper respiratory infection ... Serial CBC counts
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