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diagnosis differential causes lupus management sle systemic hematology activation algorithm cerebritis cns effusion endocarditis infectiousdiseases macrophage mas neurology pancytopenia pericardial
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Systemic lupus erythematosus ... Differential #Diagnosis #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Systemic #Lupus #Erythematosus ... CNS #neurology #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... lymphoma • Evans' syndrome ... Shrinking lung syndrome ... lymphopenia, low PLT • Anemia ... #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... ) Blood (75%): Anemia ... SLE #systemic #erythematosus ... symptoms #diagnosis #rheumatology
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Non-Infectious: • Rheumatologic ... Arthritis, Sjogren Syndrome ... Disease, Behcet Syndrome ... • Metabolic: Uremia ... Diagnosis #Causes #cardiology
Causes of Pericarditis - Differential Diagnosis Algorithm Viral: • Coxsackie • Echovirus • Adenovirus • Epstein-Barr virus
Systemic lupus erythematosus ... Post-cardiac injury syndrome ... Metabolic: • Uremia ... Algorithm #Causes #Cardiology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... Systemic lupus erythematosus ... systemic lupus erythematosus ... with leukopenia, anemia ... #Rheumatology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... iron deficiency anemia ... Acute Coronary Syndrome ... Differential #Diagnosis #Pathophysiology ... #causes #cardiology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Cholesterol emboli syndrome ... Leukocytosis, anemia ... cause + Systemic anticoagulation ... Differential #Diagnosis #cardiology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
TAFRO TAFRO syndrome ... nodes TAFRO syndrome ... systemic lupus erythematosus ... cell lymphoma Pathophysiology ... diagnosis #management #rheumatology
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