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diagnosis sle erythematosus management differential disease antiphospholipid apls arthritis causes chronic classification cll comparison cryoglobulinemia cryoglobulins diffuse druginduced henochschonleinpurpura hsp
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Differential Diagnosis Algorithm ... Reactive: - Systemic ... Lupus Erythematosus ... #Causes #Hematology ... #Oncology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... Butterfly rash, Vasculitis ... Thrombocytopenia #Lupus ... symptoms #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... #Systemic #Erythematosus ... Management #Summary #rheumatology
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 1) Suggestive clinical manifestations
1) Suggestive clinical ... - Most common systemic ... individuals - Clinical ... HSP #Diagnosis #Rheumatology ... #Peds #Pediatrics
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... months to years) Systemic ... • Immunologic Workup ... comparison #table #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular Vasculitis ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Syndrome: • Clinical ... disorder (e.g. systemic ... lupus erythematosus ... classification #rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
Related Disease Clinical ... female, asian • Systemic ... No necrosis, No vasculitis ... management #phenotypes #workup ... #treatment #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Orange or Hep C Clinical ... ’s CLL Scoring system ... Leukemia #diagnosis #workup ... #oncology #hematology
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