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SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... NEUROLOGIC - HEMOLYTIC ANEMIA ... (<1000/MM3) - THROMBOCYTOPENIA ... absence of hemolytic anemia ... #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
) Blood (75%): Anemia ... Leucopenia/lymphopenia, Thrombocytopenia ... signs #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Erythematosus - Diagnosis ... Neurological 12% - Thrombocytopenia ... - Hemolytic anemia ... Differential Diagnosis ... #differential #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... inflammation • Thrombocytopenia ... - Hemolytic anemia ... #Differential #Diagnosis ... #hematology #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
with leukopenia, anemia ... , and thrombocytopenia ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Management of Immune Thrombocytopenia (ITP) . 

#Idiopathic #Thrombocytopenic #Purpura #Immune #Thrombocytopenia #ITP #Management #Hematology
Management of Immune Thrombocytopenia ... #Idiopathic #Thrombocytopenic ... Purpura #Immune #Thrombocytopenia ... ITP #Management #Hematology
Drug-Induced Thrombocytopenia
The diagnosis of drug-induced thrombocytopenia can be made only by demonstrating resolution of thrombocytopenia once
Drug-Induced Thrombocytopenia ... The diagnosis of ... are initially diagnosed ... #Diagnosis #Hematology ... #Thrombocytopenia
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
for workup of thrombocytopenia ... indicates thrombotic thrombocytopenic ... How to approach thrombocytopenia ... , Hematology 2012 ... , p 193 #Diagnosis
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Idiopathic Thrombocytopenic ... ITP #Idiopathic #Thrombocytopenic ... #Purpura #Thrombocytopenia ... #Diagnosis #Overview ... #Hematology
Differential for the Child with Petechiae or Purpura
 - Non-thrombocytopenic
 - Thrombocytopenia

#Diagnosis #Peds #Pediatrics #Petechiae #Purpura
Purpura - Non-thrombocytopenic ... - Thrombocytopenia ... #Diagnosis #Peds ... #Differential #Thrombocytopenia