11 results
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Hydroxychloroquine ... half-life = 40 days ([HCQI ... 200ng/mL Best indications ... #SLE #rheumatology ... pharmacology #levels #lupus
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... Mild disease- Hydroxychloroquine ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Hydroxychloroquine ... and Benefits in Lupus ... recommended with other medications ... #hcq #Risks #Benefits ... #sideeffects #rheumatology
Drugs Used for the Treatment of COVID-19 Infection

** Editor Note (from ophthalmology MD input) - Hydroxychloroquine/chloroquine
Drugs Used for the Treatment ... ophthalmology MD input) - Hydroxychloroquine ... HCQ treatment would ... smfarmhosp_smfh #Drugs #Medications ... #Treatment #COVID19
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... causal drug +++, Hydroxychloroquine ... life-threatening • Treatment ... Lupusreference #druginduced ... #table #rheumatology
Hydroxychloroquine is an antimalarial & DMARD (disease modifying antirheumatic drug). It is currently being discussed as
Hydroxychloroquine ... prophylaxis and treatment ... Hydroxychloroquine ... who require this medication ... #HCQ #Pharmacology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
exam and imaging Treatment ... Sulfasalazine (SSZ), Hydroxychloroquine ... (HCQ), Leflunomide ... diagnosis #management #rheumatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
duration), Several medications ... non-essential drug/HDS treatments ... infections (HAV, HBV, HCV ... hepatitis #DILI #DrugInduced
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
constitutional symptoms • Treatment ... causal drug +++, Hydroxychloroquine ... Lupusreference #DrugInduced ... #Lupus #DIL #rheumatology ... #diagnosis #treatment
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Induced Systemic Lupus ... for 1 year of treatment ... Lupusreference #DrugInduced ... Erythematosus #medications ... differential #diagnosis #rheumatology