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differential algorithm hemophagocytic hlh lymphohistiocytosis treatment anemia aplastic atopic atopy cd4 cell ck classification creatine dermatitis dermatology diffuse dili druginduced
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Lymphoproliferative Disorders ... symptoms, unexplained hematologic ... to 50% of PTLD cases ... #oncology #diagnosis ... #management #transplant
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
- Differential Diagnosis ... Bacterial • Viral (EBV ... Myeloproliferative disorders ... #Differential #Diagnosis ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... or if a primary hematologic ... When do you do a BM ... #Differential #Diagnosis ... #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... - Differential Diagnosis ... Infectious • EBV ... #Algorithm #Causes ... #Hematology #Oncology
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Creatine Kinase - Causes ... (COVID19, CMV/EBV ... Illness Myopathy (ICU ... Neuromuscular disorders ... #differential #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Drugs, Unknown cause ... of emergency, ICU ... #management #treatment
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Toxic injury to BM ... and petechiae Causes ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... replacing the BM ... replacing the BM-common ... #differential #diagnosis ... #causes #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... for alternative causes ... HBV, HCV, HEV, EBV ... Hepatic vascular disorder ... #Algorithm #hepatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... • Autoimmune disorders ... supraclavicular node • Anterior ... classification #hematology ... #oncology #management
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