16 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... - Differential Diagnosis ... Infectious • EBV ... Lymphadenopathy #LAD ... #Hematology #Oncology
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
symptoms, unexplained hematologic ... viral load, signs ... to 50% of PTLD cases ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Drugs, Unknown cause ... of emergency, ICU ... #management #treatment
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... HCV testing - Lab ... When do you do a BM ... #Differential #Diagnosis ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Toxic injury to BM ... and petechiae Causes ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Supracondylar Elbow Fracture
• Most common elbow fracture in children, peak age 5-7 
• When looking at
posterior fat pad ... syndrome • ED Management ... MH/CCF/CWRU EM ... Radiology #XRay #Diagnosis ... #Management #Orthopedics
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
seen in 30—70% of cases ... Anti-La/SSB • ... + 90% • Anti-GBM ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
RADIAL HEAD FRACTURE 
Radial head fractures are the most common elbow fracture in adults and are
posterior fat pad ... fracture • ED Management ... MH/CCF/CWRU EM ... Radiology #XRay #Diagnosis ... #Management #Orthopedics
Mallet Finger
Absence of a fracture does NOT exclude Mallet finger, the extension function of the DIP
Finger deformity caused ... injury with axial load ... MH/CCF/CWRU EM ... Radiology #XRay #Diagnosis ... #Management #Hand
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
Lymphocytopenia DIAGNOSTIC ... CRITERIA FOR ICL ... EBV. CMV. ... #diagnosis #hematology ... #Differential #Causes