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management differential rheumatology algorithm vasculitis classification hemophagocytic hlh lymphohistiocytosis neurology oncology adultonset anemia aplastic ards atopic atopy barre cd4 cell
Pulmonary and Non-Pulmonary Causes of ARDS #Diagnosis #EM #PCC #ARDS #Differential #Algorithm #Pulmonary #NonPulmonary #Causes #Ddxof
Pulmonary and Non-Pulmonary ... Causes of ARDS ... #Diagnosis #EM # ... PCC #ARDS #Differential ... #NonPulmonary #Causes
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... to Kidney: Anti-GBM ... With associated pulmonary ... #differential #diagnosis ... #algorithm #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Ferritin >1000 ng ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... Drugs, Unknown cause ... of emergency, ICU
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... Coxsackie, CMV, EBV ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
antibody, Anti-GBM ... usually low in anti-GBM ... Goodpasture's cause ... hematuria, RBC casts ... #management #treatment
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Toxic injury to BM ... and petechiae Causes ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... for alternative causes ... HBV, HCV, HEV, EBV ... #Algorithm #hepatology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Summary Acute AIDP ... Epidemiology: • 1-2 cases ... - HIV, CMV, EBV ... Guillain-Barre Diagnosis ... #management #treatment
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
Lymphocytopenia DIAGNOSTIC ... CRITERIA FOR ICL ... EBV. CMV. ... #diagnosis #hematology ... #Differential #Causes
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... hypertension and/or drug treatment ... replacing the BM ... replacing the BM-common ... #causes #hematology
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