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diagnosis algorithm liver hematology elevated management oncology transaminitis aflp aki anemia aplastic ck creatine diffuse druginduced effusions fatty gap globulin
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
for alternative causes ... HBV, HCV, HEV, EBV ... dechallenge • Acute ... • Autoimmune hepatitis ... Diagnosis #Algorithm #hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Transaminitis - Differential ... HAV, HCV, HEV, EBV ... • Iatrogenic: DILI ... Diagnosis #causes ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... C, A, E, B, D, EBV ... #Differential # ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular Causes ... HBV, HCV, HEV, EBV ... • Iatrogenic: DILI ... #hepatitis #differential
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... > 20x normal - Acute ... normal - Infection (EBV ... #hepatology #LFTs ... transaminitis #differential
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Infectious • EBV ... Tuberculosis • Hepatitis ... Fatigue • Acute ... #Hematology #Oncology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... osmolarity If cause ... investigations depending on clinical ... ANCA, ANA, Anti-GBM ... cryoglobulins, hepatitis
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Creatine Kinase - Causes ... (COVID19, CMV/EBV ... Illness Myopathy (ICU ... renal injury, Strenuous ... #Elevated #CK #differential
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... = nonspecific (nausea ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... Liver #Pregnancy #hepatology
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Causes of Knee Effusions ... - Differential ... HSV, Varicella, EBV ... Parvovirus - Hepatitis ... Reactive Syndrome - Acute
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